ESPE Abstracts

ESPE Abstracts

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hrp0082p1-d3-22 | Adrenals & HP Axis (1) | ESPE2014

Clinical Utility of Urinary Steroid Metabolite Ratios in Children Undergoing Investigations for Suspected Disorders of Steroid Synthesis

Lucas-Herald Angela , Rodie Martina , Lucaccioni Laura , Rankin Karen , Shaikh Guftar , McNeilly Jane , Shapiro David , Ahmed Faisal

Background: Calculation of a urinary steroid metabolite ratio (uSMR) may be a useful method of improving diagnostic yield when investigating disorders of steroid hormone synthesis. Our aim was to investigate the range of uSMR in children with suspected disorders of steroid hormone synthesis.Methods: Ten ratios were calculated on steroid metabolite data analysed by GC-MS in urine samples collected between 2008 and 2010 from 94 children who were undergoing...
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ESPE Abstracts

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